Visuals that explain how a eukaryotic microbe enters the body and destroys tumors. 5-7 slides

  • Estado: Closed
  • Premio: $260
  • Propuestas recibidas: 48
  • Ganador: hassanahmad93

Resumen del concurso

Hello, IN 3-5 DAYS, I wish to create visuals that illustrate how a novel cancer therapy works . I know it's very little time but I am interested in "quick and dirty" not "3D glamorous". Here is what I would like for each slide:
1. Anterior whole body view showing tumor sites highlighted (eg. thymus, lung, ovary, skin, omentum and lymph nodes). A syringe injects "therapeutic microbes" into the thigh intramuscularly OR directly into a tumor. The microbes (nucleated cells) find their way and concentrate in the tumors but leave normal tissue alone.
2. Tumor mass view. A generic view of a tumor (a cluster of cancer cells enclosed in a protective Tumor Microenvironment) with the cellular microbes transiting easily this barrier that keeps out the body's normal immune system. As the microbes penetrate the Microenvironment, it weakens its protective shielding from the immune system.
3. Cancer cell view. close up showing membrane and nucleus at least. Endocytosis lapse illustratrion. The cancer cell endocytoses a microbe that has a "master key" to the cell membrane, invaginating it and then by pinocytosis, create a vacuole within the cytoplasm. In those vacuoles, the microbe replicates until it breaks out, fragmenting the cancer cell releasing daughter microbes and also cancer antigens and fragments that are processed by the immune system.
4. Tumor view. a) The microbial lysis is reinforced by T-cells activated by prior release of cancer fragments until the tumor Microenvironment is destroyed, leaving the microbes exposed to the body's immune system. b) Immune cells (T-cells and others) can now move into the tumor that had been weakened by the microbes and "eat" the cancer cells.
5. The immune system then eliminates the free roaming microbes that emerge from the tumor, in a matter of days.

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For inspiration, here is a link to a very glossy 3D animation of an oncolytic virus therapy. [login to view URL] There won't be enough time for that level of graphics so if only 2D is possible, that's fine.

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Please use royalty-free images if possible such as at Servier Medical Art or Wikicommons. However, if there are images at [login to view URL] that would be very useful, I could set up an account there.

Thanks

Thanks

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Comentarios del empleador

“He knew the subject matter, carefully read and addressed the project requirements and delivered on time. While others may have proposed graphics more colorful or 3D images, they did not fully grasp my requirements and some graphics overshadowed the message. Hassan provided something in very short time that conveys what I wanted.”

Imagen del perfil scottliht, United States.

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Tablero Público de Clarificación

  • imfarrukh47
    imfarrukh47
    • 9 meses atrás

    #27

    • 9 meses atrás
  • rabbiinni
    rabbiinni
    • 9 meses atrás

    Hi Scott, Hope you're doing great today. Please do review my entry #26 . Many thanks. Best, Mariya.

    • 9 meses atrás
  • iambisw
    iambisw
    • 9 meses atrás

    check entry #49 , this is what , you need in your presentation

    • 9 meses atrás
  • hr260755
    hr260755
    • 9 meses atrás

    sir can you please tell me more about it??

    • 9 meses atrás
  • iambisw
    iambisw
    • 9 meses atrás

    So you need 5 animations in total, i will try to submit them with in the time limit.

    • 9 meses atrás
    1. iambisw
      iambisw
      • 9 meses atrás

      doing them

      • 9 meses atrás
    2. iambisw
      iambisw
      • 9 meses atrás

      i have completed 60 % , just wait 2 hours, i will submit them

      • 9 meses atrás
  • CorneliaTeo
    CorneliaTeo
    • 9 meses atrás

    please check #29

    • 9 meses atrás
  • salihobouriche
    salihobouriche
    • 9 meses atrás

    Please check video #4 https://youtu.be/w1CJAugOpwI

    • 9 meses atrás
  • imfarrukh47
    imfarrukh47
    • 9 meses atrás

    in powerpoint

    • 9 meses atrás
  • shaba5566
    shaba5566
    • 9 meses atrás

    4 slide done

    • 9 meses atrás
  • salihobouriche
    salihobouriche
    • 9 meses atrás

    Working on it , i'll submit before time limit

    • 9 meses atrás
  • FinoDesignINK
    FinoDesignINK
    • 9 meses atrás

    HOLA:)

    • 9 meses atrás
    1. scottliht
      Organizador del concurso
      • 9 meses atrás

      Que tal?

      • 9 meses atrás
  • yunitasarike1
    yunitasarike1
    • 9 meses atrás

    WORKING

    • 9 meses atrás

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